Acute myeloid leukemia in a patient with constitutional 47,XXY karyotype
نویسندگان
چکیده
Klinefelter syndrome (KS), a 47,XXY chromosomal abnormality, has been shown to be associated with a number of malignancies, but has not been linked to acute leukemias to date. We present a case of a 54-year-old male diagnosed with acute myeloid leukemia (AML) with monocytic differentiation, whose cytogenetic and subsequent FISH analyses revealed a constitutional 47,XXY karyotype. We also review and discuss relevant prior literature.
منابع مشابه
Klinefelter syndrome and acute basophilic leukaemia--case report.
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عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2015